Ceramide-mediated transport of chloride and bicarbonate across phospholipid membranes.

نویسندگان

  • William A Harrell
  • Marie Liesel Bergmeyer
  • Peter Y Zavalij
  • Jeffery T Davis
چکیده

The sphingolipid, ceramide 1, facilitates transport of Cl(-) and HCO(3)(-) anions across lipid bilayers under conditions where large transmembrane pores are not formed. Ceramide's 1,3-diol unit is essential for both binding and transporting these anions.

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عنوان ژورنال:
  • Chemical communications

دوره 46 22  شماره 

صفحات  -

تاریخ انتشار 2010